Astros vs. Guardians Prediction
The official MLB play for April 21, 2026: the pick, the price it was sent at, the stake and the final result.
Astros
GuardiansThe Play
The official MLB play for Astros vs. Guardians on April 21, 2026 was Astros ML (+123) (moneyline), sized at 0.50u.
Every official play is logged here at the price it was sent and graded against the final score.
Result
The MLB pick on Astros vs. Guardians graded as a LOSS for -0.50u.
More From These Teams
Every Gridiron & Wine pick involving the Astros or the Guardians is logged on their team archive pages.
About This Archive
Every Gridiron & Wine MLB official play is logged and published — wins, losses, and pushes alike. No deletions. The full track record is verified here, and every graded play is in the MLB pick archive.
More on our MLB plays on the MLB picks page, or see the glossary for any unfamiliar terms.