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NFL · Week 1 · September 13, 2026

Arizona Cardinals vs Los Angeles Chargers Final — September 13, 2026

Arizona Cardinals logo
Arizona Cardinals
26
FINAL
Los Angeles Chargers logo
Los Angeles Chargers
14
Sunday, September 13 · 4:25 PM ETSoFi Stadium · indoorsWeek 1

Final score and result vs the closing line

Arizona Cardinals 26, Los Angeles Chargers 14

Arizona Cardinals won by 12.

The pre-game matchup

The Cardinals visited the Chargers at SoFi Stadium on Sunday, September 13 at 4:25 PM ET in Week 1.

Last season (2025), the Cardinals had the 23rd-ranked offense by EPA per play (expected points added per snap) and the 27th-ranked defense. Meanwhile, the Chargers had the 25th-ranked offense and the 7th-ranked defense. When the Cardinals have the ball, a 23rd-ranked offense (−0.018 EPA per play) meets a 7th-ranked defense (−0.083 allowed); when the Chargers have it, a 25th-ranked offense (−0.023) meets a 27th-ranked defense (+0.088 allowed).

By success rate (the share of plays that gain expected points), the Cardinals offense was at 43.0% (22nd) and the Chargers offense at 43.1% (19th). Through the air, the Cardinals averaged +0.023 EPA per dropback (20th) against a Chargers pass defense ranked 9th; the Chargers averaged +0.001 (23rd) against a Cardinals pass defense ranked 26th. The Cardinals scored 20.9 points per game (23rd) and allowed 28.7 (29th); the Chargers scored 21.6 (20th) and allowed 20.0 (9th). The new season has no games yet, so these are last season's full-season numbers; rosters change over the offseason.

The Chargers closed as 9.5-point favorites at home against the Cardinals. The spread opened at Chargers -10.5. The total closed at 47, down from 47.5 at the open. After removing the vig, the closing moneyline (Cardinals +372, Chargers -495) prices the Cardinals at 20% and the Chargers at 80%.

Written from the numbers available before kickoff.

Tale of the tape

Arizona Cardinals logoCardinals
ChargersLos Angeles Chargers logo
Offense
EPA per playexpected points added per snap
−0.01823rd
−0.02325th
Success rateshare of plays that gain expected points
43.0%22nd
43.1%19th
EPA per dropbackpassing plays, sacks and scrambles included
+0.02320th
+0.00123rd
EPA per rushdesigned runs
−0.11329th
−0.06624th
Points per gamescored
20.923rd
21.620th
Defense
EPA per play allowedexpected points the defense gives up per snap
+0.08827th
−0.0837th
Success rate allowedshare of opponent plays that gain expected points
48.5%31st
41.4%7th
EPA per dropback allowedpass defense
+0.16426th
−0.0639th
EPA per rush allowedrun defense
−0.02025th
−0.1153rd
Points allowed per gameallowed
28.729th
20.09th

Full 2025 regular season (last season), captured before kickoff. League rank in small type (32 teams); the gold side ranks higher. Bars show rank, longest = 1st. Source: play-by-play via the public NFL Lab tables (raw EPA, not opponent-adjusted).

Coaching and tendencies

Cardinals head coachMike LaFleur
Chargers head coachJim Harbaugh
StaffCardinalsChargers
Head coachMike LaFleurJim Harbaugh
Offensive coordinatorNathaniel HackettMike McDaniel
Defensive coordinatorNick RallisChris O'Leary

Season to date before kickoff, from play-by-play (regular season). Ranks out of 32 teams; for style stats with no better or worse, rank 1 = highest. Coaching staff: Wikipedia contributors (CC BY-SA 4.0).

Injury report

Cardinals
  • Garrett Williams CBOutAchilles
  • Isaiah Adams GOutKnee
  • Dadrion Taylor-Demerson SOutRibs
Chargers
  • Tuli Tuipulotu DEQuestionableHip

Starters (and the primary passer) on the game's official injury report, as of the latest report captured before kickoff.

Travel and schedule

Cardinals travel350 mi564 km
VenueIndoorsSoFi Stadium

The Cardinals travel about 350 miles.

Distance is straight-line from each team's home stadium; time-zone change is at kickoff. Rest counts days since each team's previous game.

Head-to-head

The teams have met 3 times since 2015: the Cardinals won 1 and the Chargers 2. In the most recent meeting (October 21, 2024), the Cardinals won 17-15; the Cardinals averaged +0.036 EPA per play; the Chargers averaged +0.049 EPA per play.

DateScoreSpreadTotalEPA/play
Oct 21, 2024Chargers 15, Cardinals 17
Cardinals won
Chargers -1
Cardinals covered
44
under
Cardinals +0.036 · Chargers +0.049
Nov 27, 2022Chargers 25, Cardinals 24
Chargers won
Chargers -2.5
Cardinals covered
48.5
over
Cardinals +0.058 · Chargers +0.069
Nov 25, 2018Cardinals 10, Chargers 45
Chargers won
Chargers -14
Chargers covered
43.5
over
Cardinals −0.321 · Chargers +0.354

The last five meetings since 2015, most recent first. Spread and total are the nflverse closing lines.

Closing line and line movement

Spreadmoved 1
OpenChargers -10.5 (-106)
Cardinals +10.5 (-112)
CloseChargers -9.5 (-108)
Cardinals +9.5 (-112)
Totaldown 0.5
Open47.5 (o -107 / u -113)
Close47 (o -111 / u -109)
Moneyline
OpenCardinals +425 18%
Chargers -595 82%
CloseCardinals +372 20%
Chargers -495 80%

Consensus of US sportsbooks. Open = first line after both teams' previous games; Close = consensus at kickoff. Percentages are the moneyline's no-vig market-implied chances.

Teams

Arizona Cardinals

Los Angeles Chargers

Gridiron & Wine graded a pick on this game: see the archived pick.

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